IMPACT OF DEMOGRAPHIC VARIABLES ON THE RISK OF PANCREATOGENIC ENCEPHALOPATHY IN PATIENTS WITH NUTRITIONAL PANCREATONECROSIS

Resume. Aim. Study of the dependence degree risk developing pancreatogenic encephalopathy (PEP) on demographic variables in patients with nutritional pancreatic necrosis. Materials and methods. A single-center prospective cohort non-randomized study was conducted basis Faculty Surgery Clinic Volgograd State Medical University period from 2010 to 2020. To determine significance influence a patient-dependent factor PEP, ROC analysis used. Logistic regression used PEP against background combination several covariates. Results. The included 429 necrosis alimentary origin. comparative incidence carried out depending gender age, trigger disease (alcohol-associated versus non-alcoholic necrosis) comorbid background. It has been proven that significant factors increase are age over 60 years (p = 0,04), alcohol-associated < 0,001) cardiovascular pathology - ischemic heart 0,001). statistically model effect developed, which makes it possible calculate this complication particular patient. Conclusions. Significant include years, alcoholic pancreatitis, presence coronary artery developed logistic personalized during hospitalization patient